Since 2001 as Consultant in Medical Oncology for breast cancer at The Christie he has developed a fully integrated practice of research, education and service innovation. He created and developed the Breast Cancer Research Team, the highest recruiter to clinical trials in the UK and is one of the founding members of The Manchester Breast Centre, leading the Clinical Studies Group whose key goal is to introduce new agents and treatment approaches into the clinic.
He is a member of the National Cancer Research Institute Breast Cancer Clinical Studies Group. In 2011 he was appointed Clinical Director of the The NIHR Cancer Research UK Christie Research Facility and secured fudning from NIHR for an Experimental Medicine Facility. In 2016 The NIHR Manchester Clinical Research Facility was formed and Professor Wardley leads cancer experimental medicine across Greater Manchester.
He leads the strategic aims of increasing world class research across Greater Manchester and delivering EM to a more of the population access.
He is also The Director of Christie/Greater Manchester Cancer Systemic Anti-Cancer Therapy, and has devised many service innovations including outreach SACT research and Enhanced Supportive Care. He was awarded a Manchester Academic Health Science Centre/University of Manchester Chair in 2016.